process

Unfolded protein response (UPR)

The UPR aims to fold good proteins, despite the ER stress, as long as the level of stress does not become too great or lasts too long. The UPR causes an increase in the volume of the ER lumen, so that proteins can still be folded, despite lack of space caused by the accumulation of wrong proteins. At the same time these misfolded proteins are broken down by proteasomes, or recycled into aggressomes. In this way, the cell can continue to do its job despite the stressors that act on it

Ref: The contributor did not provide a reference

0 confidence points
0 comments
Added on Jun 14, 2022 by Barbara Van De Keer
Edited on Jul 1, 2022 by No update

Join Ninatoka!!

NinatoKa's goal is to support you as a therapist in unravelling the illness pathway from symptoms to cause, and to help you detect potential interventions.

Go to Explore to start your discovery!

Go to Learn to scroll through newly added data.

Go to Contribute to contribute to the Ninatoka database.

You can rate content up or down and add comments if you agree or disagree.