process

Pepsinogen to pepsin conversion

Pepsinogen is a powerful and abundant protein digestive enzyme secreted by the gastric chief cells as a proenzyme and then converted by gastric acid in the gastric lumen to the active enzyme pepsin. Anticholinergics, histamine H2-receptor antagonists, and vagotomy decrease pepsinogen secretion.

Ref: https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/pepsinogen

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Added on Jul 10, 2022 by Barbara Van De Keer

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