condition

Vagotomy

Vagotomy or genetic disruption of the α7 gene significantly exacerbates TNF responses to inflammatory stimuli and sensitizes animals to the lethal effects of endotoxin (15), suggesting that cholinergic anti-inflammatory signals transmitted via the efferent vagus nerve play a role in maintaining immunological homeostasis.

Ref:
CHRISTOPHER J. CZURA, MAURICIO ROSAS-BALLINA, KEVIN J. TRACEY, CHAPTER 3 - Cholinergic Regulation of Inflammation, Editor(s): Robert Ader, Psychoneuroimmunology (Fourth Edition), Academic Press, 2007, Pages 85-96, ISBN 9780120885763, https://doi.org/10.1016/B978-012088576-3/50007-1. (https://www.sciencedirect.com/science/article/pii/B9780120885763500071).

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Added on Jul 10, 2022 by Barbara Van De Keer
Edited on Jul 10, 2022 by Barbara Van De Keer

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