concept

Nuclear factor erythroid 2-related factor (NRF2)

Nrf2 governs the gene expression of endogenous antioxidant synthesis and ROS-eliminating enzymes in response to various electrophilic compounds that inactivate the negative regulator Keap1.

Ref:
Kasai S, Shimizu S, Tatara Y, Mimura J, Itoh K. Regulation of Nrf2 by Mitochondrial Reactive Oxygen Species in Physiology and Pathology. Biomolecules. 2020 Feb 17;10(2):320. doi: 10.3390/biom10020320. PMID: 32079324; PMCID: PMC7072240.

20 confidence points
0 comments
Added on May 25, 2022 by Barbara Van De Keer
Edited on May 14, 2023 by Barbara Van De Keer

Join Ninatoka!!

NinatoKa's goal is to support you as a therapist in unravelling the illness pathway from symptoms to cause, and to help you detect potential interventions.

Go to Explore to start your discovery!

Go to Learn to scroll through newly added data.

Go to Contribute to contribute to the Ninatoka database.

You can rate content up or down and add comments if you agree or disagree.