concept

SHBG (sex hormone binding globulin)

The principal function of SHBG has traditionally been considered to be that of a transport protein for sex steroids, regulating circulating concentrations of free (unbound) hormones and their transport to target tissues. Recent research suggests that SHBG has functions in addition to the binding and transport of sex steroids.

Ref:
Wallace IR, McKinley MC, Bell PM, Hunter SJ. Sex hormone binding globulin and insulin resistance. Clin Endocrinol (Oxf). 2013 Mar;78(3):321-9. doi: 10.1111/cen.12086. PMID: 23121642.

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Added on Sep 9, 2022 by Barbara Van De Keer
Edited on Sep 19, 2023 by Barbara Van De Keer

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