concept

Siglec

Cell surfaces in the immune system are richly equipped with a complex mixture of glycans, which can be recognized by diverse glycan-binding proteins. The Siglecs are a family of sialic-acid-binding immunoglobulin-like lectins that are thought to promote cell–cell interactions and regulate the functions of cells in the innate and adaptive immune systems through glycan recognition.

Ref:
Cell surfaces in the immune system are richly equipped with a complex mixture of glycans, which can be recognized by diverse glycan-binding proteins. The Siglecs are a family of sialic-acid-binding immunoglobulin-like lectins that are thought to promote cell–cell interactions and regulate the functions of cells in the innate and adaptive immune systems through glycan recognition.

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Added on May 16, 2022 by Barbara Van De Keer
Edited on Apr 19, 2023 by Barbara Van De Keer

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