concept

JAM-A (Junctional Adhesion Molecule A)

Endothelial and epithelial tight junctions are made up of three major transmembrane protein families: (1) occludins, (2) claudins, and (3) junction-associated molecules (JAMs), in addition to cytoplasmic accessory proteins, which include the zonula occludens protein ZO-1.42,43

Ref:
Cecilia Choy, Josh Neman, Chapter 6 - Role of Blood–Brain Barrier, Choroid Plexus, and Cerebral Spinal Fluid in Extravasation and Colonization of Brain Metastases, Editor(s): Josh Neman, Thomas C. Chen, The Choroid Plexus and Cerebrospinal Fluid, Academic Press, 2016, Pages 77-102, ISBN 9780128017401, https://doi.org/10.1016/B978-0-12-801740-1.00006-8. (https://www.sciencedirect.com/science/article/pii/B9780128017401000068)

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Added on Sep 24, 2022 by Barbara Van De Keer
Edited on Oct 29, 2022 by Barbara Van De Keer

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