concept

IgE antibodies

IgE is the least abundant serum immunoglobulin and is involved with protection from parasitic disease and allergic responses. Pathologically, IgE induces type I hypersensitivity reactions through activation of mast cells and basophils and the induction of TH2 responses resulting in atopic diseases.

Ref:
Ignacio Sanz, Scott A. Jenks, Kevin S. Cashman, 26 - Structure and Derivation of Autoantibodies, Editor(s): Daniel J. Wallace, Bevra Hannahs Hahn, Dubois' Lupus Erythematosus and Related Syndromes (Ninth Edition), Elsevier, 2019, Pages 340-354, ISBN 9780323479271, https://doi.org/10.1016/B978-0-323-47927-1.00026-8. (https://www.sciencedirect.com/science/article/pii/B9780323479271000268)

20 confidence points
0 comments
Added on Sep 28, 2022 by Barbara Van De Keer
Edited on Sep 28, 2022 by Barbara Van De Keer

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