concept

Damage associated molecular pattern (DAMP)

Damage-associated molecular patterns (DAMPs) are endogenous danger molecules that are released from damaged or dying cells and activate the innate immune system by interacting with pattern recognition receptors (PRRs). Although DAMPs contribute to the host's defense, they promote pathological inflammatory responses.

Ref: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117512/

20 confidence points
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Added on Jul 16, 2022 by Barbara Van De Keer
Edited on Jul 16, 2022 by Barbara Van De Keer

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