concept

Electron transport chain

KEY POINTS ABOUT THE ELECTRON TRANSPORT CHAIN ▪ The electron transport chain is located in the mitochondrial inner membrane and contains several different kinds of electron carriers: flavin mononucleotide, iron-sulfur proteins, coenzyme Q, heme-containing cytochromes, and copper ions. ▪ Three large multiprotein complexes serve as proton pumps by harnessing the energy from electron flow through the ETC to oxygen; in turn, the chemiosmotic energy in the proton gradient that is created by the pumps is coupled to the synthesis of ATP by the ATP synthase complex. ▪ ATP regulates its own synthesis and the flow of electrons through respiratory control; if ATP synthesis slows down, electron transport slows down and vice versa. ▪ Cytosolic NADH cannot pass through the mitochondrial membrane, so it shuttles its electrons through the glycerol phosphate shuttle and the malate-aspartate shuttle. ▪ ATP and ADP are transported in exchange for each other by the ATP/ADP translocase.

Ref:
John W. Pelley, 7 - Citric Acid Cycle, Electron Transport Chain, and Oxidative Phosphorylation, Editor(s): John W. Pelley, Elsevier's Integrated Biochemistry, Mosby, 2007, Pages 55-63, ISBN 9780323034104, https://doi.org/10.1016/B978-0-323-03410-4.50013-4. (https://www.sciencedirect.com/science/article/pii/B9780323034104500134)

0 confidence points
0 comments
Added on Jul 1, 2022 by Barbara Van De Keer
Edited on Sep 27, 2022 by Barbara Van De Keer

Join Ninatoka!!

NinatoKa's goal is to support you as a therapist in unravelling the illness pathway from symptoms to cause, and to help you detect potential interventions.

Go to Explore to start your discovery!

Go to Learn to scroll through newly added data.

Go to Contribute to contribute to the Ninatoka database.

You can rate content up or down and add comments if you agree or disagree.