concept

Agtr2 (angiotensin II type 2 receptor)

Angiotensin II is the most biologically active effector peptide of the RAS and binds to either the angiotensin II type 1 (Agtr1) receptor located within the renal tubule to increase sodium reabsorption or the Agtr2 receptor to decrease sodium reabsorption.

Ref:
James S.M. Cuffe, Sarah L. Walton, Karen M. Moritz, Chapter 15 - The Developmental Origins of Renal Dysfunction, Editor(s): Cheryl S. Rosenfeld, The Epigenome and Developmental Origins of Health and Disease, Academic Press, 2016, Pages 291-314, ISBN 9780128013830, https://doi.org/10.1016/B978-0-12-801383-0.00015-3. (https://www.sciencedirect.com/science/article/pii/B9780128013830000153)

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Added on Nov 22, 2022 by Barbara Van De Keer

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