concept

H+ (Intracellular hydrogen ion)

Intracellular hydrogen ion (H+) buffering power, conventionally defined as the amount of acid or base that would have to be introduced into the cell cytosol to decrease or increase ipH by one pH unit, is generally said to increase as intracellular pH (ipH) decreases. This implies that the cell has a lesser capability to resist acute acid or base perturbations at its steady state ipH than at any lower ipH.

Ref:
Saleh AM, Rombola G, Batlle DC. Intracellular H+ buffering power and its dependency on intracellular pH. Kidney Int. 1991 Feb;39(2):282-8. doi: 10.1038/ki.1991.34. PMID: 2002641.

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Added on Jan 9, 2023 by Barbara Van De Keer
Edited on Jan 9, 2023 by Barbara Van De Keer

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