process

T4 to t3 conversion

Thyroxine (T4) is the main secretory product of the thyroid follicle cells and is converted to the active hormone, triiodothyronine (T3), in the tissues under the influence of microsomal deiodinase enzymes, which remove the iodine from the “outer” ring (5'-deiodination).

Ref:
Brian L. Furman, Thyroxine, Editor(s): S.J. Enna, David B. Bylund, xPharm: The Comprehensive Pharmacology Reference, Elsevier, 2007, Pages 1-4, ISBN 9780080552323, https://doi.org/10.1016/B978-008055232-3.62758-8.

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Added on Apr 16, 2022 by Barbara Van De Keer
Edited on Aug 8, 2022 by Barbara Van De Keer

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