enzyme

Kynurenine aminotransferase (KAT)

KATs catalyze the irreversible transamination of KYN to KYNA and 3-hydroxykynurenine (3-HK) to xanthurenic acid (XA), thus controlling the routing of KYN and 3-HK to their corresponding branches of the kynurenine pathway.

Ref:
Castro-Portuguez R, Sutphin GL. Kynurenine pathway, NAD+ synthesis, and mitochondrial function: Targeting tryptophan metabolism to promote longevity and healthspan. Exp Gerontol. 2020 Apr;132:110841. doi: 10.1016/j.exger.2020.110841. Epub 2020 Jan 16. PMID: 31954874; PMCID: PMC7053056.

20 confidence points
0 comments
Added on Mar 4, 2023 by Barbara Van De Keer
Edited on Mar 4, 2023 by Barbara Van De Keer

Join Ninatoka!!

NinatoKa's goal is to support you as a therapist in unravelling the illness pathway from symptoms to cause, and to help you detect potential interventions.

Go to Explore to start your discovery!

Go to Learn to scroll through newly added data.

Go to Contribute to contribute to the Ninatoka database.

You can rate content up or down and add comments if you agree or disagree.