enzyme

Aspartate aminotransferase (AST/GOT)

The levels of aspartate aminotransferase (AST/GOT) and alanine aminotransferase (ALT/GPT) in serum can help people diagnose body tissues especially the heart and the liver are injured or not. ------------ Aspartate aminotransferase (AST, EC 2.6.1.1) exists in human tissues as two distinct isoenzymes, one located in the cytoplasm (c-AST), and the other in mitochondria (m-AST). Striated muscle, myocardium, and liver tissues are the main sources of AST.

Ref:
Huang XJ, Choi YK, Im HS, Yarimaga O, Yoon E, Kim HS. Aspartate Aminotransferase (AST/GOT) and Alanine Aminotransferase (ALT/GPT) Detection Techniques. Sensors (Basel). 2006 Jul 31;6(7):756–82. PMCID: PMC3894536. ------------- Panteghini M. Aspartate aminotransferase isoenzymes. Clin Biochem. 1990 Aug;23(4):311-9. doi: 10.1016/0009-9120(90)80062-n. PMID: 2225456.

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Added on Nov 5, 2023 by Barbara Van De Keer
Edited on Nov 5, 2023 by Barbara Van De Keer

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