concept

Pancreatic alpha cells

Low Glucose Stimulates Glucagon Release from α Cells in the Islets of Langerhans The α cells make up 25% of the islets of Langerhans and secrete glucagon, a 29-amino-acid peptide, in response to hypoglycemia. The α cells synthesize proglucagon which is then cleaved by a proprotein convertase to form glucagon. Glucagon restores blood glucose levels by mobilizing glucose primarily from the liver. Glucagon also affects adipose tissue.

Ref:
Joseph Feher, 9.4 - The Endocrine Pancreas and Control of Blood Glucose, Editor(s): Joseph Feher, Quantitative Human Physiology, Academic Press, 2012, Pages 799-809, ISBN 9780123821638, https://doi.org/10.1016/B978-0-12-382163-8.00087-6. (https://www.sciencedirect.com/science/article/pii/B9780123821638000876)

20 confidence points
0 comments
Added on Jun 5, 2022 by Barbara Van De Keer
Edited on Sep 25, 2022 by Barbara Van De Keer

Join Ninatoka!!

NinatoKa's goal is to support you as a therapist in unravelling the illness pathway from symptoms to cause, and to help you detect potential interventions.

Go to Explore to start your discovery!

Go to Learn to scroll through newly added data.

Go to Contribute to contribute to the Ninatoka database.

You can rate content up or down and add comments if you agree or disagree.